Abstract: To determine the clinic valune of left ventricular systolic function measured by digitial subtraction ventriculography （DSA）. radionuclide ventriculography （RNA） and echocardiogrphy methods （UCG）, 53 subjects with coronary heart disease and 16 normal controls were recuited. The results showd that, regardless the wall motion status, EF measured by DSA and UCG modified Simpson’s rule. Half-ellipse cylinder method and RNA have good correlation （respectively, r=0.84, 0.79. 0.72, P＜0.0001）. Regarding the abnormality of left ventricular wall motion, comparitive analysis of three methods mentioned showd that EF measured by DSA and UCG modified Simpson’s rule. Half-ellipse cylinder method and RNA have good correlation （respectively, r=0.81, 0.82, 0.58） in abnormal anterior wall motion group. EF measured by the methods mentioned above have-faily bad correlation in abnormal inferior wall motion. EF measured by UCG was higher than it by DSA.