不同配伍的异丙酚静脉麻醉在人工流产及宫腔镜检查中的应用

The apply of different compatibility of propofol used for intravenous anesthesia in induced abortion and uteroscope examine

  • 摘要: 目的: 观察异丙酚与芬太尼、氯胺酮、曲马多复合麻醉用于无痛人流和宫腔镜检查的效果,探讨合理的麻醉配方。方法: 90例行无痛人流和宫腔镜检查的患者,随机分为3组,异丙酚分别复合芬太尼(F组)、氯胺酮(K组)及曲马多(T组)静脉麻醉,每组30例。观察各组异丙酚用量、意识消失时间、停药后清醒时间、清醒后独立离院时间;监测Bp、HR、SpO2、术中及术后的不良反应。结果: 异丙酚用量三组间无显著性差异。K组意识消失时间短(P<0.05);F组清醒时间和离院时间长(P<0.05)。F组SpO2下降幅度及下降率高(P<0.01);低血压、心率减慢发生率高于K、T组(P<0.05,P<0.01)。F组术后站立眩晕率高(P<0.05);3组均有个别患者发生恶心、腹痛及欣快感,无尿潴留及皮肤瘙痒发生。结论: 异丙酚与芬太尼、氯胺酮、曲马多复合麻醉用于无痛人流和宫腔镜检查,镇痛效果均好。但氯胺酮异丙酚和曲马多异丙酚诱导和清醒更加迅速,呼吸循环抑制轻,不良反应未见增加,是安全合理的配方选择。

     

    Abstract: Objective: To observe the effect of propofol anesthesia with fentanyl,kentamine,tramadol in artifician abortion and Hysteroscope Examine. Methods: Ninety patiens were randomly divided into three groups with 30 cases each: Propofol compound fentanyl(group F), kentamine(group K) and tramadol(group T) intravenous anesthesia separately.The propofol dosage,consciousness loss time, wake-up time,independenly leave hospital time were recorded. Observing Bp,HR, SpO2 and side effects during intro-and post-operative. Results: The dosage of propofol in three groups wasn’s significant difference. Consciousness loss time in group K was shorter(P<0.05), wake-up time and independenly leave hospital time were longer in group F than that in the others(P<0.05). SpO2 down range and rate were significant higher in group F (P<0.01). Bp and HR decrease were significant higher in group F (P<0.05, P<0.01). Postoperative vertigo was higher in group F(P<0.05). The incidences of nausea, bellyache and euphoria were low in three groups. Conclusion: The analgesic effects are all good in three groups that compound anesthesia of propofol. But propofol-kentamine and propofol- tramadol are more rapidly in inducement and recovery without significant side effects, they are safe and suitable choice in artifician abortion and Uteroscope Examine.

     

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