Abstract: Objective To study the new methods for improving the quality of life（QOL） in cancer patients. Methods One hundred and thirty-seven cancer patients,admitted to our hospital from January 2010 to October 2011,were randomly divided into treatment group（n=68） and control group（n=69）.Patients in treatment group underwent one course ofαbrain wave biofeedback therapy and those in control group received routine nursing.Scores and total scores of their QOL before and after treatment were compared according to the EORTIC-30（version-3）. Results The overall QOL,somatic function（SF）,emotional function（EF）,fatigue（FA）,nausea and vomiting（NV）,appetite and sleep were significantly better in treatment group after α brain wave biofeedback therapy than in control group（P＜0.01）. Conclusion Alpha brain wave biofeedback therapy can effectively improve the QOL in cancer patients by alleviating their symptoms and signs and increasing their physiological and psychological functions.