间接创伤对幼年鼠颞下颌关节早期影响的光镜观察

Primary study indirect trauma on temporomandibular joint of young rat

  • 摘要: 目的:探讨间接创伤对幼年鼠颞颌关节早期影响的组织学变化。方法:实验用1月龄Wistar大白鼠32只,通过下颌角造成颞下颌关节间接创伤,然后在创伤后24h、1周、2和4周应用光镜方法对其颞下颌关节进行观察。结果:与正常组比较,光镜下可见创伤后24h髁状突表面纤维软骨松解、碎裂。伤后1~2周髁状突、关节盘表层成纤维细胞增生,纤维软骨层增厚。伤后4周可见盘突粘连。结论:间接创伤可致幼年鼠颞下颌关节组织的损伤并引起关节盘及髁状突表面纤维软骨出现增生性修复变化,长期的变化尚有待进一步研究

     

    Abstract: Objective: The aim of this study was to evaluate the effect of indirect trauma on temporomandibular joint of young rat. Methods: The effect of indirect trauma to the temporomandibular joint is analysed by means of an experimental model The trauma, applied from an angle glenoid fossa direction, produed injury of the temporomandibular joint. Light microscope was studied on these young wistar rats at different time. Results: 24 h post-trauma. All the temporomandibular joint components showed signs of injury. 1~2 week post-trauma. Indirect trauma of young rat can lead to many fibroblasts appeared on surface of condylar. 4 week post-trauma. It was shown the adhesion between disc and condyle.Conclusion: Indirect trauma can lead to proliferative repair changes of the articular disk and the articular surface of the condyle to young rat.

     

/

返回文章
返回