Abstract: Objective: To promote recognition of pulmonary aspergillosis and develop appropriate clinical treatment for the disease. Methods: The clinical features of 21 cases of pulmonary aspergillosis were analyzed in our hospital. Results: All 21 patients had primary diseases.9 patients were administered glucocorticoids chronically（42.9%）;18 were administered antibiotics for more than 3 weeks（85.7%）;9 were treated with mechanical ventilation（42.9%）;8 were treated with deep venous catheter（38%）;and 6 had leucopenia（28.6%）.Among the 21 cases,3 patients had allergic pulmonary aspergillosis（14.3%）,5 had parasitic pulmonary aspergillosis（23.8%）,and 13 had invasive pulmonary aspergillosis（61.9%）.5 patients died（23.8%）.16 were cured or improved（76.2%）. Conclusion: Most patients with pulmonary aspergillosis have primary diseases accompanied with risk factors.Diagnoses are made based on past medical history,chest radiography and sputum culture,and confirmed according to aspergillus found in pulmonary tissue.Different treatments such as glucocorticoids,surgery or medication should be used according to different types of pulmonary aspergillosis.