Abstract: Objective:In order to study the effect of left ventricular hypertrophy（LVH） on left ventricular remodelling after acute myocardial infarction（AMI）.Methods:26 patients with anterior wall AMI were prospectively examined by serial echocardiography in the following seqnence: the first, seventh day, one and three months after being admitted in hospital. left ventricular end-diastolic volume index （LVEDVI）, left ventricular end-systolic volume index （LVESVI）, ejection fraction （EF）, basal interventricular septum（ivs） and posterior wall thickness （PW） were measurd. According to their baseline LV thidckness patients were divided into group I （LVH） and groupⅡ （NLVH）（IVS+pw）=24±1 mm and 20±2 mm respectively). Results:Our study showed that at the end of 3 months, LVEDVI, LVESVI increased in GroupⅡ and didn't in Group Ⅰ （P＜0.05） （LVEF）. Conclusion:This suggested that baseline LVH is an important factor governing infarct expansion and LV after AMI remodeling.