血脂及脂蛋白在心血管疾病糖尿病及肿瘤等不同疾病中的意义

杨秀; 高艳红; 田亚平

血脂及脂蛋白在心血管疾病糖尿病及肿瘤等不同疾病中的意义

Significance of serum lipid and lipoprotein levels in patients with cardiovascular disease,diabetes and cancer

摘要

摘要: 目的探讨血脂的变化在心血管类疾病、糖尿病及肿瘤等不同疾病中的意义。方法采用日立7600全自动生化分析仪对146例心血管疾病、71例糖尿病、74例肿瘤患者和76例正常人血清的总胆固醇(CH)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-CH)、低密度脂蛋白胆固醇(LDL-CH)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)、脂蛋白a(Lpa)共7项指标进行检测。结果糖尿病组ApoA1、LDL P<0.01,CH、HDL P<0.05;心血管疾病组ApoA1、HDL P<0.01,CH、LDL P<0.05;肿瘤组lpa P<0.05,CH、TG、ApoA1、HDL、LDL P<0.01。结论不同疾病的血脂水平变化不同,可通过对不同患者血脂水平观察及早发现疾病。

Abstract: Objective To study the significance of serum lipid level in patients with cardiovascular disease,diabetes and cancer. Methods Serum levels of total cholesterol（CH）,high-density lipoprotein（HDL）,low-density lipoprotein（LDL）,triglycerides（TG）,apolipoprotein A1（ApoA1）,apolipoprotein B（ApoB） and lipoprotein（lpa） were measured in 146 patients with cardiovascular disease,71 patients with diabetes,74 patients with cancer and 76 healthy controls with a Hitachi automatic biochemistry analyzer. Results The serum levels of CH,ApoA1,LDL,HDL,Lpa,TG,and ApoB were significantly higher in patients with cardiovascular disease,diabetics and cancer than in controls（P＜0.05）. Conclusion The serum lipid level is different in patients with different diseases which can be early discovered by measuring the serum lipid level.

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