Abstract: Objective: To compare the effect of diagnosis for renal tuberculosis by 3 kind of serological diagnosis methods. Methods: The specific antibody in the serum were detected by immunochromatography and ELISA. Results: The positive rate of anti-LAM antibody were 59.6%, 0% and 0% respectively in the serum of 52 patients with renal tuberculosis, 105 healthers and 126 patients with renopathy; The positive rate of anti-38ku protein and cytoplasmic membrane antibody were 82.7%, 0.9% and 2.4% respectively; The positive rate of anti-PPDantibody were 76.9%, 8.5% and 11.1% respectively.By the united detection of anti-LAM antibody and anti-38ku antibody, the positive rate of renal tuberculosis was 88.5%. Conclusion: The rapid test of anti-LAM and Anti-38ku antibody could be applied to the preliminary diagnosis and differentiation diagnosis of real tuberculosis.