牛磺酸对实验动物免疫功能及游泳耐力的影响

Effect of taurine on immunity and swimming physical endurance in mice

摘要: 目的: 研究牛磺酸对机体的免疫功能和运动耐力的影响。方法: 以小鼠作为研究对象,用于检测指标的实验动物均分为三组,杏仁露组、杏仁露+牛磺酸组和对照组,采用灌胃方式,14 d后以脾指数、迟发性变态反应、血清溶血素水平、B淋巴细胞和T淋巴细胞增殖指数和游泳时间作为观察指标。结果: 牛磺酸可增强小鼠的SRBC-DTH水平和使脾指数增高,并可显著刺激小鼠脾内B淋巴细胞的增殖,增强其B淋巴细胞的溶血素抗体的分泌,延长小鼠的游泳时间;但对T细胞的增殖无明显作用。结论: 该结果表明牛磺酸可调节实验动物的免疫功能和增强其运动耐力。

Abstract: Objective: To study the effects of Taurine on immunity and Swim tolerance of mice.Methods: The mice used for experiment were divided into three groups（almond juice,almond juice add Taurine and control）.After 14 days by gavage,The spleen-index,SRBC-DTH,HA,T lymphocyte stimulus index,B lymphocyte stimulus index and Swimming physical endurance were measured.Results: The result indicated that Taurine could enhance the level of HA and SRBC-DTH.It also could increase the spleen-index,B lymphocyte stimulus index and improve the swim tolerance of mice,but it had no effect on T lymphocyte stimulus index.Conclusion: Taurine can improve the immunity and Swimming physical endurance of mice.