Abstract: Objective: To investigate indications of different ultrafiltration, simple and convenient blood shunt, key techniques and special precautions. Methods: To review the clinical data of 364 patients who used different ultrafiltration and analyze the ultrafiltrated volumes, hematocrits （Hct） and serum potassium. Results: The ultrafiltrated volumes was （1 109±781）ml and Hct changed from 0.248±0.049 to 0.320±0.067 during coventional ultrafiltration（CUF）.By modified ultrafiltration（MUF）, the ultrafiltrated volumes （28.4±12.8）ml/kg and Hct from 0.219±0.040 to 0.335 0.076. With blood concentrate, arterial pressure raised gradually and duration of endutracheal intubation was obviously shortened in postoperation. By zero-balanced ultrafiltration（Z-BUF）, the ultrafiltrated volumes was （2 060±860）ml and serm potassium changed from（6.69±0.46）mmol/L to （5.32±0.38）mmol/L. In 36 cases the totally fluid volumes is balance or negative balance in the end of CPB, the most one–93 ml/kg. In 9 patients with anemia, Hb didn’t changed or increased. Infant whose weight was less 10kg accepted transfusion with 100～150 ml RBC. Conclusion: Both CUF and MUF can concentrate blood quickly, MUF yet improve early hemodynamics and organs function. MUF may be the chiefly choice in CPB of infant. Z-BUF is efficient to reduce high serum potassium.