Abstract: Objective To systematically evaluate the relation between plasma lipid level and venous thrombosis. Methods A metaanalysis of 10 papers on random control study about the effect of plasma lipid level on venous thrombosis was carried out using Review Manager4.2. Results The plasma high-density lipoprotein level was higher in case group than in control group（P＜0.000 01）, triglyceride level was lower in case group than in control group（P＜0.000 01）, and there was no significant difference in plasma total cholesterol and low-density lipoprotein level between the two groups（P＞0.05）. Conclusion Dyslipidemia is a risk factor for venous thrombosis.