Abstract: Objective: To explore measures on disaster rescue in modern time through diseases investigation of disaster area and rescue experinece during the mid and late period of disaster.Methods: Investigated and statistically analyzed the incidence of diseases of 32 300 civilians in Dujiangyan disaster area during 5-30 days after Wenchuan Earthquake,retrospectively summrized the problems encountered during the medical rescue work.Results: During the mid and late period of Wenchuan Earthquake,the major diseases occurred were upper respiratory tract infection（URI）,skin diseases,mild truama and digestive diseases.The highest incidence rate was infection of the upper respiratory tract.The rate of incidence of skin diseases rised obviously.Diarrhea was the major digestive diseases.Unprepared to the high incidence rate of skin diseases and the insufficient drug reserve for some chronic diseases such as hypertension,heart diseases and diabetes were challenges meeted during the medical rescue.Conclusion: Sufficient drug reserve for infection of the upper respiratory tract,skin diseases,mild truama and digestive diseases is very important to medical rescue for heavy earthquake.Morever,certain drug reserve for some common chronic diseases is also necessary.