Abstract:
Objective To analyze the MR imaging features and to assess the role of MRI in the diagnosis of pancreatic neuroendocrine tumors.
Methods MR imaging features of 18 patients with pathologically-confirmed pancreatic neuroendocrine tumors were retrospectively analyzed.MR scanning included SE T1WI,fat-suppressed T1WI,FSE T2WI,and fast multiplanar spoiled gradient recalled(FMPSPGR) wave before and after the contrast medium,Gd-DTPA,was used.
Results Most lesions were detected at T1WI(66.7%,12/18) and fat-suppressed T1WI(78.6%,11/14).Lesions found at FMPSPGR(84.2%,16/19) had low signals,and lesions found at T2WI(66.7%,12/18) had high signals.Lesions found at FMPSPGR and fat-suppressed T1WI were clearer than those found at routine T1WI and T2WI.Dynamic contrast-enhancement scanning showed moderate and intense homogenous enhancement signals in 10 tumors at the arterial,portal venous and delayed phases.The intensity of tumor signals was still higher than that of normal pancreatic parenchyma.Peripheral nodule enhancement with gradual centripetal enhancement,moderate homogenous enhancement,delayed homogenous enhancement,and cystic changes with ring enhancement were observed in 3,2,2,and 2 tumors,respectively. One tumor located in the pancreatic body had hepatic metastasis.
Conclusion Multi-sequence and dynamic contrast-enhanced MRI plays an important role in the diagnosis of pancreatic neuroendocrine tumors.