Abstract: Objective: To explore the therapy of hypertension with emotional disorder patients. Methods: 65 emotional disorder patients with hypertension were divided into 2 groups,the one was given antihypertension medicine,the other plus Fluoxertin. Results: the symptoms of depression and anxiety disorder were obviously alleviated in Fluoxertin group,the side effection were mild. Conclusion: Fluoxertin was effective in hypertension patients with emotional disorder.