Abstract:
The process of revascularization of denervated muscle in 41 rabbits has been studied by gross observation, histolgical and electronic microscope survey. This study shows that during the first day after transplantation the muscle is entirely avascularized. It consists of thin peripheral zone of surviving muscle fibers and large central area of severe ischenic muscle. Part of the endothelial cells of the original blood vessels are destroyed.
Revascularization from the surrounding tissues is began on the 7th day after grafting. Scattered capillaries begin to grow into graft and a fairly normal relationship between new capillaries and original vessles is established. On the 120th~240th days after transplantaion the musclefib ers and revascularized vessels recover to normal. The vasculature of the mature graft includes elements from the "new" and reutilized original blood vessels.