497例经典型不明原因发热患者病因分析
Clinical analysis of the causes in 497 patients suffered from the fever of unknown origin with the classic type
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摘要: 目的: 探讨经典型不明原因发热（fever of unknown origin,FUO）的病因及诊断。方法: 对解放军总医院2000年1月2005年4月间497例经典型FUO患者的病因进行分析。结果: 其病因分布为:感染性疾病（189/497,38.0%）、结缔组织病和炎性血管性疾病（165/487,33.2%）、恶性肿瘤性疾病（58/497,11.7%）、其他疾病（46/497,9.3%）及未明确诊断的疾病（39/497,7.8%）。在感染性疾病、结缔组织和炎性血管性疾病及恶性肿瘤疾病中所占比例最大的分别为结核感染（51.8%,98/189）、成人斯蒂尔病（51.5%,85/165）和淋巴瘤（56.9%,33/58）。不典型淋巴瘤、合并阻塞性肺炎的肺癌患者及坏死性淋巴结炎易于误诊。结论: 经典型FUO患者的病因分布存在特征性,这对于FUO的临床诊断有一定的指导意义。Abstract: Objective: To analysis the cause characteristics in the fever of unknown origin（FUO） patients with the classic type.Methods: The clinical data of 497 cases with classic FUO admitted to the Chinese PLA general hospital from January 2000 to April 2005 were analyzed.Results: The cause distribution of the classic FUO were: the infective diseases（38.0%,（189/497））,connective tissue diseases（165/497,33.2%）,malignant tumor（58/497,11.7%）,the other diseases（（46/497）,9.3%）and unknown diseases（39/497,7.8%）.The dominated diseases in the infective,connective tissue and malignant tumor diseases were tuberculosis infection（98/189,51.8%）,adult Still’s disease（51.5%,85/165）and lymphoma（56.9%,（33/58））separately.The non-typical lymphoma,lung cancer with obstructive pneumonia and necrotizing hyperplastic lymphadenopathy were the main diseases in the classic FUO misdiagnosis.Conclusion: The cause characteristics of classic FUO were helpful to their clinical diagnosis.
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