高海拔地区健康军人唾液指标测定

Normal reference values of parameters in saliva of healthy servicemen at high altitude areas

摘要: 目的探讨高海拔地区健康军人唾液指标正常参考范围。方法受试者按海拔高度分为3 700m组(n=49)、4 300m组(n=57)、4 500m组(n=36)、5 300m组(n=21)及平原对照组(1 400m组,n=20),采集其唾液标本,应用高效液相色谱分析法测定唾液多项生化指标。结果随海拔高度增加,各项指标水平有不同程度增高;与平原对照组比较,除Mg²⁺、K⁺以外,5 300m组各项指标均显著增高,差异有统计学意义(P<0.01或P<0.05)。结论初步确定了不同海拔地区唾液指标正常参考范围,为高原地区兵员作训标准的制定提供了参考。

Abstract: Objective To study the normal reference values of parameters in saliva of healthy servicemen at high altitude areas. Methods Subjects were divided into 3 700m group,4 300m group,4 500m group,5 300m group and plain control group（1 400m group）.Biochemical parameters were detected in saliva samples with high performance liquid chromatogram（HPLC）. Results The levels of biochemical parameters in saliva increased with the increasing altitude.Except for Mg²⁺ and K⁺,the levels of other biochemical parameters in saliva were significantly higher in 5 300m group than in plain control group（P＜0.05）. Conclusion The normal reference values of different parameters in saliva are initially established,which may provide reference for working out criteria for the training of servicemen at high altitude areas.