Abstract: Six cases of inflammatory fibromatoid polyp of alimentary tract, 1. in the lower esophagus, 2. in the stomach and 3. in ileum were reported. Macroscopically, they were polypoid masses protruding into the lumen, ranging from 1 to 8cm in diameter, Microscopically, the lesions were found chiefly in the submucosa and were composed of numerous fibroblasts, loosely arranged collagenous fibres, network of small capillaries and varying amount of inflammatory cells of various types, including eosinophils, numerous in some cases. S-100 protein and vimentin were used for revealing the histogenesis, the former being negative and the latter positive. The lesion is most likely to be composed of inflammatory granulation tissue rather than true neoplasm. In order to avoid unnecessery extensive operation pre-or intra operative biopsy is indicated. To fit in with the histopathological changes, the term of "Inflammatory fibromatoid polyp" is suggested.