Abstract:
Objective To investigate the effect of acute blood pressure elevation on artery rigidity.
Methods Dopamine was used to increase 30%, 50%, 70% of the systolic blood pressure, respectively, in 30 New Zealand rabbits.Elasticity coefficient(Eρ), rigidity index(β)and artery compliance(AC) of the abdominal aorta were measured with ultrasonic tracer technique.
Results The Eρ was 84.33±8.41, 120.74±11.49, 121.33±9.59, 121.64±9.32, respectively, the β was 8.74±0.61, 10.48±0.71, 10.59±0.50, 10.65±0.54, respectively, and the AC was 0.58±0.40, 0.39±0.26, 0.39±0.25, 0.39±0.26, respectively, in the control, 30%, 50% and 70% blood pressure elevation groups.
Conclusion Artery rigidity can be affected by acute blood pressure elevation and increases with increasing blood pressure, but maintains relatively stable when the blood pressure reaches a certain extent.