原发性高血压患者左室肥厚的分型及其相应左心功能的特点

Types of Hypertensive Left Ventricular Hypertrophy and Their Influence on Left Ventricular Function

  • 摘要: 以超声心动图观察321例原发性高血压患者中150(46.7%)例伴左室肥厚(LVH)者的肥厚类型及相应左心功能特点,并与104例健康者对照。结果发现,向心性、不对称性及扩张性肥厚的构成比分别为47.3%、42.0%和10.7%。扩张性肥厚组左室射血分数较低。向心性及不对称性肥厚组左心舒张功能减退且后者的改变较明显。

     

    Abstract: One hundred and fifty patients with hypertension who have left ventricular hypertrophy (LVH) were evaluated with echocardiography and compared to 171 hypertensives without LVH and 104 normal controls. The incidence of three types of LVH are: concentric 47.3%, inappropriate 42.0% and dilatec 10.7%. The left ventricular ejection fraction decreased only in dilatic LVH (53.1 ± 11.8%, P<0.01). The early peak filling velocity and early to late peak filling velocity ratio were decreased significantly both in concentric (0.64 ± 0.24m/s and 1.03± 0.51) and inappropriate (0.65±0.18m/ s and 0.89± 0.42) LVH, while comparable to the normal controls (0.69± 0.23m/s and 1.11± 0.53). But the two indexes are increased in the dilatic LVH (0.79± 0.39m/s and 1.15±0.99). These results indicate that: the left ventricular systolic function is affected in dilatic LVH, and it decreases both in concentric and inappropriate LVH. The reason for the increment of deastolic function in dilatic LVH is still unknown.

     

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