肝移植患者细菌感染的初步观察

Observation of bacterial infection among liver transplant recipients

  • 摘要: 目的: 了解肝移植患者的菌群感染特点及药敏结果,指导临床工作。方法: 回顾性分析2003年12月2004年12月期间肝移植患者所分离的病原菌及其耐药性。结果: 15例肝移植患者的各种送检标本共分离出细菌44株,G-杆菌占63.6%(铜绿假单胞菌居多),G+球菌占27.3%(表皮葡萄球菌为主),同时药敏结果表明G-杆菌对左旋氧氟沙星、泰能、头孢吡肟、环丙沙星和丁胺卡那敏感性较好,而对头孢三代、氨曲南和奥格门丁耐药性较高;G+球菌对万古霉素、替考拉宁无耐药株,而对青霉素耐药性高达90%。结论: 加强对肝移植病人的细菌监测,指导临床有效抗感染治疗。

     

    Abstract: Objective: To find out the trait of bacteria infection and the drug-sensitivity results and direct the clinical assignment in liver transplant recipients.Methods: The bacteria cultured from the liver transplant recipient during the period of 2003.12-2004.12 and their drug-resistance were analyzed.Results: A total of 44 strains bacteria were cultured from various specimen of 15 liver transplant recipients,63.6% were Gram-negative bacteria(most of them were Pseudomonas aeruginosa ),(27.3%) were Gram-positive ones(the major were S.Epidermidis),the Gram-negative bacteria were more sensitive to Levofloxacin、Impenem、Cefepime、Ciprofloxacin and Amikacin but more resistant to third generation cephalosporin、Aztreonam and Amoxicllin/Clavulanic acid,the Gram-positive bacteria were sensitive to Vancomycin and Teicoplanin but 90% of them were resistant to Penicillin.Conclusion: The effective treatment of bacteria pneumonia after liver transplantation relies on more attention paid to bacteria control.

     

/

返回文章
返回