原发性卵巢平滑肌肉瘤及纤维肉瘤临床病理分析

Clinicopathologic analysis of primary ovarian leiomyosarcoma and fibrosarcoma

  • 摘要: 目的:探讨原发性卵巢肉瘤的临床特点、诊断、治疗及预后。方法:分析我院2例原发性卵巢肉瘤患者的病例资料,并复习相关文献。结果:本组2例原发性卵巢肉瘤患者均未能早期确诊,病情发展快,手术难度大,预后差(1例已死亡)。结论:原发性卵巢肉瘤的早期诊断困难,主要依靠病理,核分裂像多见,病理性核分裂像可见,免疫组化显示Vimentin(+)。该病恶性程度高,治疗效果及预后均差,可辅助化疗及放疗。

     

    Abstract: Objective:To investigate the clinical characteristics,diagnosis,therapy and prognosis of primary ovarian sarcoma.Methods: Retrospectively the information of two cases of primary ovarian sarcoma in our hospital and pertinent literatures were analyzed and reviewed.Results: The two cases of primary ovarian sarcoma developed rapidly,could not be diagnosed at early stage,was hard to surgery and had worse prognosis.Conclusion: To diagnose earlily primary ovarian sarcoma is very difficult.Its diagnosis depends mainly on pathology.The image of caryocinesis of this disease mostly can be seen and the pathologic image of caryocinesis can also be observed.Immunohistochemistry result displays vimentin(+).The degree of malignancy of this disease is very high.Its therapeutic efficacy and prognosis are both worse.chemotherapy and radiotherapy can be helpful to be combined with surgery.

     

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