Abstract: Objective To study the pathogenesis,early diagnosis and best treatment of cesarean scar pregnancy（CSP）. Methods Clinical data about 10 CSP patients admitted to our hospital from January 2005 to January 2010,including age,pregnancies and deliveries,interval between disease onset and cesarean,initial symptoms,auxiliary examination findings,and therapies,were retrospectively analyzed. Results Ten CSP patients at the age of 32.3±4.4 years and 10 284 normal pregnancy patients were admitted to our hospital from January 2005 to January 2010 in our hospital.Of the 620 ectopic pregnancy patients admitted,10 were CSP patients,accounting for 1.6% of all the ectopic pregnancy patients.The interval between disease onset and last cesarean was 6.1±3.9 years.The most common clinical symptoms of CSP were amenorrhea and vaginal bleeding.Of the 10 CSP patients,3 were misdiagnosed as intrauterine early pregnancy and 1 as trophocyte tumor in other hospital,6 who were diagnosed and treated in our hospital received systemic or local injection of methotrexate（MTX） and combined hysteroscopy and laparoscopy treatment.All the patients were discharged. Conclusion CSP is easy to be misdiagnosed.Its early diagnosis should be made according to the clinical and auxiliary examination findings.Individual therapy is the key to CSP.Combined hysteroscopy and laparoscopy can achieve satisfactory outcomes.