Abstract: Objective To study the clinical characteristics of different gender patients with acute myocardial infarction（AMI）. Methods Two hundred AMI patients were divided in male group（n=100） and female group（n=100） and their clinical characteristics were retrospectively analyzed. Results The average age of patients in female group was greater than that of those in male group（P＜0.05）.The incidence of hypertension and diabetes mellitus was higher in female group than in male group（P＜0.05）.No difference was observed in hyperlipemia,infarction size,characteristics of coronary lesions,and arrhythmia between the two groups（P＞0.05）.The Killip classification≥Ⅲ and the mortality during hospital stay time were higher in female group than in male group（P＜0.05）. Conclusion The number of risk factors for female AMI patients is greater and the mortality during hospital stay time of them is high.