冠状动脉药物支架再狭窄形式分析

金琴花; 盖鲁粤; 杨庭树; 王禹; 刘宏斌; 陈练

冠状动脉药物支架再狭窄形式分析

Coronary restenosis morphology after intracoronary drug eluting stents implantation

摘要

摘要: 目的:分析冠状动脉支架置入后造影复查的影像资料,寻找不同药物支架再狭窄的特点。方法:收集冠状动脉介入治疗后造影复查再狭窄患者121例,共159处病变,进行再狭窄形式分析。结果:裸支架(BMS)和药物支架(DES)后再狭窄病变局限性再狭窄分别占39.80%和70.49%(P<0.001);弥漫性再狭窄病变分别占60.20%和29.51%(P<0.001);三种不同类型DES(Cypher,Taxus和Firebird)再狭窄形式没有差异,局限性再狭窄分别为83.33%,55.56%和75.00%(P=0.070);弥漫性再狭窄分别占16.67%,44.44%和25.00%,(P=0.070)。结论:①DES改变了以往BMS再狭窄模式,由弥漫型转为局限型;②不同种类的药物支架再狭窄形式没有差异。

Abstract: Objectives:To evaluate the morphology of in-stent restenosis after different kinds of stents.Methods: 121 Patients with 159 restenosis lesions after intracoronary interventional therapy were included in this study.Restenosis morphology of different kinds of stents were analysed.Results: The focal restenosis in drug eluting stent（DES） and bare metal stent（BMS） was 39.80% and 70.49% respectively（P=0.000）;Diffuse restenosis was 60.20% and 29.51%（P＜0.001）.The morphology of the different kinds of DES（Cypher,Taxus and Firebird） was similar（focal restenosis was 83.33%,55.56% and 75.00%,P=0.070;diffuse restenosis was 16.67%,44.44% and 25.00%,P=0.070）.Conclusion: DES changed the morphology of in-stent restenosis,from diffuse restenosis to focal restenosis;Different DES has the similar morphology of restenosis.

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