Abstract: Objective: To study the protective effects of Erigeron breviscapus on renal peroxisome from ischemia reperfusion injury in rat.Methods: The activities of superoxide dismutase,glutathione peroxidase,catalase and malondial dehyde in preparations of renal peroxisomes were respectively measured.To study the protective effects of Erigeron breviscapus on kidney from ischemia reperfusion injury in rat.Results: The activities of catalase,GPX,total SOD of peroxisomes were significantly enhanced in ischemia-reperfusion kidney in rat treated with Erigeron breviscapus（P＜0.01）.MDA concentration was significantly decreased（P＜0.01）.Conclusion: Erigeron breviscapus can significantly protect renal peroxisomes from ischemia reperfusion（in rat）.