Abstract: Objective: To observe and assess the effects of cryopreserved alloskin graft on excised burn wound in the major burned patients in their early stage hosp-italized from January 1987to April 2002. Methods: One hundred and twelve with burned patients undergoing allograft during burn shock stage were retrospectively analyzed，including the time of wound excision, the area and location of wound excis-ion，bleeding volume during escharectomy，the ratio of autologous microskin and excised wound，the first time of dressing chang postoperation，skin taken-rate，etc.Furthermore，the viability of cryopreserved alloskin was checked before graft.Results: There was 20% higher in viability of cryopreserved alloskin by vitrification than that by slow cooling.Meanwhile，the improved cryopreserved alloskin possessed very good quality and might survive for longer time with high skin taken-rate after graft.Conclusion: The graft of microautoskin and cryopreserved alloskin with high viability following early escharectomy is one of the essential treatments for patients with major burn.