氦-氧混合气治疗重症支气管哮喘的临床研究

The clinical study of breathing heliox in severe asthmatics

摘要: 目的：观察重复利用氦气的循环式氦-氧混合气辅助呼吸装置对哮喘患者的作用。方法：选择8例重症支气管哮喘急性发作患者，通过重复利用氦气的循环式氦-氧混合气辅助呼吸装置呼吸氦-氧混合气（79%He），观察肺功能及血气的变化。结果：氦-氧混合气可以降低气负荷，促进氧合，增大呼气流速；起效迅速，但后续效应短暂。结论：循环式氦-氧混合气辅助呼吸装置设计思路比较理想，可以节省氦气的消耗，取得了较好的临床疗效。

Abstract: Objective:The study evaluated the effects of breathing helium-oxygen in asthmatic patients.Methods:Eight asthmatic patients breathing heliox（FiO₂:21%） for 120 minutes with assisted respirator of recycled using helium. The datas of pulmonary function test, arterial blood gas values of the patients were recorded. Results:The results demonstrate that heliox can reduce breathing work, ameliorate oxygen diffusion and expired flow, but the duration is very short after stopping breathing heliox.Conclusion:The study suggests that the assisted respirator of recycled using helium can save helium distinctively, and the clinical applications demonstrate that the instrument is useful for treating severe asthmatic patients.