Abstract: Objective: To determine the efficacy of cytological examination in detecting endometrial carcinoma by two kinds of equipment. Methods: The cells of endometria were obtained by means of Ori Endometyial Sampler and Ori Endometyial Brush.Diagnostic uterine curettage was done simulfaneourly. Results: （1）1093 cases including 895 cases by Endometyial Sampler and 198 cases by Endometrial Brush were observed, the success rate of performation was 100%; （2）The satisfactory rates of specimens collected with Endometrial Sampler and Endometrial Brush were 81.1%（726/895） and 82.8%（164/198）, respectively, P=0.063. Meanwhile, the rate of satisfactory samples obtained from diagnostic uterine curettage was 93.2%; ⑶When using the histological of endometrial carcinoma as the diagnostic standard, the diagnostic accordance rate of the cytology with the histological pathology was 83.3%, false positive rate and false negative rate were 0.8%, and 18.6%, respectively. Conclusion: The Ori Endometrial Sampler and Ori Endometrial Brush, used to detecting endometrial carcinoma, could collect the satisfactory specimens with high sensitivity, high specificity, high rate of diagnostic accordance rate. Besides, it was convenient and had less blood loss, with almost no pain to use these equipment. The material was used only once to avoid cross infection. Therefore, these method were safe and effective and these could be introduced into clinical application.