50例老年期痴呆患者EEG动态研究

Serial Observation of EEG in the Aged with Dementia: Report of 50 Cases

  • 摘要: 本文报告50例经临床、辅助检查确诊的老年期痴呆患者,EEG进行了2~27年计2~25次动态观察,揭示了50例患者智能正常阶段做EEG均在正常范围,出现智能减退症状时血管病性痴呆组EEG异常率为39%。Alzheimer病性痴呆组为58%、混合型为33%。确诊为痴呆时血管病性痴呆组异常率达89%,Alzheimer病性痴呆组为67%、混合型组为70%。而血管病性痴呆组不对称比率大干Alzheimer病性痴呆组。α指数随痴呆的加重而逐渐减少,本资料说明,早期观察EEG对老年期痴呆的早期诊断具有一定的价值,动态观察可为诊断提供依据。

     

    Abstract: Fifty cases of dementia in the elderly were follwed-up by EEG for 2-24 times within 27 years. These results showed that in all patients with normal EEG revealed normal intelligence. Patients with slight disturbance of intelligence, their EEG abnormal rates were found 39%. 58% and 33% respectively in the group of vascular dementia, Alzheimer’s diseases and mixed dementia, when patients confirmty diagnosed as dementia, their EEG abnormal rates in hese three groups increased significantly. The results were 89%, 67% and 70% respectively, and he asymmetry ratio of the vascular dementia was higher than that of Alzheimer’s diseases. The decreasing of Alpha index(αI) is along with the severity of dementia. When αI equals to zero, the EEG in patients with severe dementia was observed generalized slow activity. We conclude hat sequential followup of EEG and αI are the feasible and valuable parameters for the early diagonosis of dementia and provide scien-tific basis of prognosis.

     

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