鲎试剂检查醒脑静注射液细菌内毒素的探讨
Detection of bacterial endotoxin in Xingnaojing injection with Tachypleus Amebocyte lysate
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摘要: 目的 探讨用鲎试剂检查醒脑静注射液细菌内毒素方法。方法 根据《中国药典》2005年版Ⅱ部收载的细菌内毒素检查法的要求进行实验。结果 醒脑静注射液经10倍稀释时不干扰鲎试剂与细菌内毒素的凝胶反应。结论 细菌内毒素检查法适用于检测醒脑静注射液的内毒素。Abstract: Objective To study the method for the detection of bacterial endotoxin in Xingnaojing injection with Tachypleus Amebocyte lysate（TAL）.Methods Experiments were performed according to the bacterial endotoxin tests covered in Chinese Pharmacopeia 2005（part 2）.Results Xingnaojing injection did not interfere with its gel reaction to the bacterial endotoxin when it was diluted 10-fold.Conclusion Bacterial endotoxin test can be used to detect bacterial endotoxin in Xingnaojing injection.
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