Abstract: objective:to build an objective principle to distinguish the difference of the discharge patterns between Gpi and Gpe. Methods: The discharge of pallidum neurons is recorded and stored. The spike is demarcated after operation to compute the frequency （f） of the single-unit discharge, Bust Index （BI）, Pause Index （PI） and Pause Ratio （PR）. It is compared between the f,BI, PI and PR of Gpi and of Gpe. Compute Sensitivity（Se）, Specificity（Sp）, mistake diagnosis（α）, omission diagnosis（β）, and Accuracy（Ac） when f、BI、PI and PR are used as guideline respectively to differentiate discharge patterns between Gpi and Gpe. Results: The f、BI、PI、PR of Gpi is 96±43Hz、2.31±1.81、0.05±0.05、0.27±0.28 respectively. The f、BI、PI、PR of Gpe is 59±27、0.88±0.63、0.20±0.14、1.54±1.17 respectively. When f、BI、PI and PR is used as the index respectively to differentiate Gpi and Gpe neuron, the Se、Sp、α、βand Ac is 0.84、0.78、0.77 and 0.93;0.64、0.79、0.88 and 0.87;0.36、 0.21、0.12 and 0.13;0.16、0.22、0.23 and 0.07;0.72、0.79、0.80 and 0.90. Conclusion: PR is a better index to distinguish Gpi and Gpe.