老年高血压合并冠心病患者的心率变异性分析

Analysis of heart rate variability of elderly patients with hypertension combined with coronary heart disease

  • 摘要: 目的 了解老年高血压(EH)病合并冠心病(CHD)患者心率变异性的特点及其临床意义。方法 选择EH患者34例及EH合并CHD患者32例,老年健康对照组38例,青年健康对照组51例,进行24h动态血压和动态心电图检查,对两组患者心率变异性(HRV)参数及室性心律失常发生率进行对照分析。结果 与对照组比较,EH组和EH合并CHD组HRV均降低(P<0.05),其中EH合并CHD组HRV降低更为显著(P<0.01);与对照组比较,EH组和EH合并CHD组室性心律失常的发生率增加(P<0.05),其中EH合并CHD组室性心律失常的发生率增加更为显著(P<0.01)。结论 反映自主神经活性变化的HRV可作为高血压患者预后的重要指标之一。尤其对EH合并CHD的患者,临床上除降压治疗外,还应根据HRV的改变情况给予积极改善自主神经功能的治疗。

     

    Abstract: Objective To investigate the characteristics of heart rate variability(HRV)and clinical values in elderly patients with essential hypertension(EH)complicated by coronary heart disease(CHD). Methods 24-hour dynamic electrocardiogram was performed to examine the HRV in 34 patients with EH,32 patients with EH complicated by CHD,38 old healthy people as an old-aged control group and 51 middle-aged healthy people as a middle-aged control group.Their HRV and incidence of ventricular arrhythmia were comparatively analyzed. Results The HRV was lower in the two patient groups,especially in the group with EH complicated by CHD,than in the two control groups(P<0.05).The incidence of ventricular arrhythmia was higher in the two patient groups than in the two control groups(P<0.01). Conclusion HRV showing autonomic nerve activity is one of the important indexes for the prognosis of hypertension patients.Other treatment modalities should be considered in addition of hypertension-reducing treatment for such patients,especially for those with EH complicated by CHD in order to improve their autonomic nerve function.

     

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