68例乳腺黏液腺癌病理特征及预后分析

Clinicopathologic observation of the mucinous breast adencarcinoma and its relationship to prognosis

  • 摘要: 目的: 探讨乳腺黏液腺癌的临床病理特征及其与预后的关系。方法: 收集我院乳腺黏液腺癌手术标本68例,对组织学类型,淋巴结转移状态,ER、PR、NSE表达与预后之间的关系进行回顾性分析。结果: 68例中单纯型46例,混合型22例,单纯型ER、PR、NSE阳性率分别为88.37%、79.07%和95.35%,混合型ER、PR、NSE阳性率分别为68%、5 6%和88%,大于2cm肿瘤5年生存率较小于2cm者低(P<0.05),淋巴结转移患者5年生存率较无淋巴结转移者低(P<0.05),单纯型和混合型5年生存率有显著性差异(P<0.05)。结论: 肿瘤大小、组织学类型和淋巴结转移状态是决定乳腺黏液腺癌预后的重要因素,单纯型黏液腺癌的腋下淋巴结转移率较混合型低,其预后相对于混合型黏液腺癌患者好。

     

    Abstract: Objective: To investigate the Clinicopathologic character of the mucinous breast Adencarcinoma and its relationship to prognosis. Methods: 68 patients with the mucinous breast adencarcinoma were analysed retrospectively in the tumor size,the histological type, the lymph node state, the level of ER,PR, NSE. Results: Of the 68 tumors,43 were of the pure type and 25 of mixed type. The rates of ER-positive and PR-positive in the pure type were 88.37% and 79.07%, respectively, and the rates of NSE-positive was 95.35%. The rates of ER-positive and PR-positive in the mixed type were 68% and 56%, respectively, and the rates of NSE-positive was 88%. 5-year survival rate was associated with size of tumor (P<0.05), lymph node metastasis (P<0.05) histological subtype(P<0.05). Conclusion: The size of tumor and the lymph node state and histological type are importance factors in the prognosis of the patients with the mucinous breast adencarcinoma. The patients with pure mucinous adencarcinoma had a lower rate of axillary node metastasis and a better prognosis than those of patients with the mixed type mucinous carcinoma.

     

/

返回文章
返回