Abstract: Objective: To observe the curative effect and safety of temporary cardiac pacing（TPI） and intra-aortic balloon pump（IABP） and to discuss the relative factors for mortality in patients with acute myocardial infarction（AMI） after treatment with TPI and IABP. Methods: Twenty-one patients with AMI treated with both TPI and IABP in our department from 2003 to 2008 were retrospectively analyzed.Multivariate logistic regression analysis was performed to determine the relative factors for mortality. Results: Ten out of the 21 patients died with a mortality rate of 47.6%.The causes of death were found to be severe refractory cadiogenic shock,infection complicated by multiple organ failure,refractory ventricular arrhythmia,and cardiac rupture,etc.Multivariate logistic regression analysis showed that cardiac function and urine output could predict the risk of death. Conclusion: Treatment with TPI and IABP can result in a high mortality rate of patients with AMI.Urine output（＜0.5mL·kg-1·h-1）,excessive use of vasoactive substances such as dopamine,ejection fraction value（＜40%） are the predicting factors for the risk of death.