Abstract: Objective: To evaluate the clinical profile of total venous anesthesia using fentanyl-propofol-reminfentanil. Methods: 44 ASA Ⅰ-Ⅱadult patients undergoing elective laryngo-microsurgery under the suspension laryngoscopy were randomly divided into two groups.All patients were induced with fentanyl-propofol followed by topical anesthesia of larynopharynx with 2% dicaine.Group A（n=22） received general anesthesia with remifentenyl-propofol infusion.Group B（n=22） received general anesthesia with fentanyl-isoflurane during mantenance.The time from administration of anesthetics stopped until eye opening and tracheal extubation,and Modified Aldrete recovery score 10 minute after administration of anesthetics stopped were recorded.（ Results: （1））Haemodynamic index didn’t vary significantly in both group after induction.during placed.The incidence of Cardiovascular stress reactions to placed microlaryngoscope or extubation in group B were significantly higher than that in group A.（（2）Time） from administration of anesthetics stopped to tracheal extubation wasn’t different in A and B group.Recovery time of emergence was shorter in group A than in group B.Recovery quality was much more better in group A than in group B.（ Conclusion: Compared） with general anesthesia using fentanyl-isoflurane.Total venous Anesthesia with fentanyl,remifentenyl and propofol was a better method for suspension laryngoscope than general anesthesia with fentanyl-isoflurane.It can achieved the optimal hemodynamic stability during anesthesia induction and maintenance,and better recovery profile from anesthesia.