前列地尔注射液两种给药方式所致静脉炎的临床观察与护理

Clinical observation and nursing of patients with phlebitis caused by two administration routes of alprostadil injection

摘要: 目的探讨降低前列地尔注射液所致静脉炎的输液方式。方法选取需要接受前列地尔注射液治疗的患者60例,将患者随机分为两组,试验组采用将前列地尔注射液10μg加入0.9%氯化钠注射液100ml中滴注给药;对照组采用0.9%氯化钠注射液100ml静滴中滴斗入给药。两组患者均接受1次/d的该药静脉输液治疗10d,比较两组患者输液后静脉炎发生情况。结果试验组静脉炎的发生率为6.67%,对照组静脉炎的发生率为46.67%,两组差异有统计学意义(P<0.05)。结论采用静脉滴注的方法进行前列地尔注射液输液治疗,较滴斗入的方法显著减少静脉炎的发生。

Abstract: Objective To explore the infusion methods to reduce phlebitis caused by alprostadil injection. Methods Sixty patients were randomly divided into experiment group and control group.Patients in experiment and control groups received intravenous infusion and drip of 10μg alprostadil injection in 100ml saline,respectively,once a day for 10 days.Occurrence of phlebitis in the two groups was compared. Results The incidence of phlebitis caused by intravenous infusion and drip of alprostadil injection was 6.67% and 46.67%,respectively（P＜0.05）. Conclusion Intravenous infusion of alprostadil injection is much better than intravenous drip in reducing phlebitis.