低分子肝素治疗恶性肿瘤并发深静脉血栓疗效观察

Clinic therapeutic effect of L-M-W-H treating malignancy complicated by deep venous thrombosis

摘要: 目的:探讨恶性肿瘤伴发深静脉血栓形成(DVT)的治疗对策。方法:150例并发DVT的恶性肿瘤患者全部接受了溶栓治疗,观察其疗效。结果:溶栓治疗总有效率84.7%,治疗前后血浆D-二聚体阳性率分别为97.3%及7.3%(P<0.05)。出现DVT症状到开始溶栓治疗的时间间隔<24 h者,溶栓治疗有效率为96.9%,24～72 h者为69.8%,>72 h者为30.0%。结论:低分子肝素治疗恶性肿瘤并发深静脉血栓,疗效确切。

Abstract: Objective:To analyze the treatment of malignancy complicated by deep venous thrombosis（DVT）.Methods: 150 cases of malignancy complicated by DVT were all received thrombolysis therapy,and the therapeutic efficacy was observed.Results: The total effective rate of thrombolysis therapy was 84.7%,the express rate of plasma D-dimer before and after therapy was 97.3% and 7.3% respectively（P＜0.05）.The effective rate of thrombolysis therapy was 96.9%.69.8% and 30.0% when the interval between the thrombolysis therapy and the initial symptom was ＜24 h,24～72h,＞72h respectively.Conclusions: The therapy of Low-Molecular-Weight-Heparins has a certain effect to the DVT complicated by malignancy.