五种标志物检测对胸腹水诊断价值的探讨

Clinical significance of five parameters in pleural and ascitic fluid

  • 摘要: 本文报告71例不同疾病患者胸腹水中乳酸脱氢酶(简称LDH)、腺苷酸脱氨酶(Ade-nosie deaminae ADA)、纤维蛋白元降解产物(简称FDP)、铁结合蛋白(iron binding protein IBP)和C-反应性蛋白(C-redction protein CRP)五项指标结果观察,其浓度依次是结核性胸膜炎>炎症>恶性肿瘤>肝癌>肝硬化、肝炎。前三者之间(除ADA外)、后两者之间五项检测均值无明显差异(P>0.05),而后两者与前三者之间差异显著(P<0.01)、恶性肿瘤与前两者ADA含量有显著差异(P<0.01);炎症CRP检测率明显高于结核性胸膜炎和其它疾病。认为联合检测弥补了单项测定的不足,提高了鉴别诊断。

     

    Abstract: Ascitic and pleura fluid samples from 22 patients with hepatitis, cirrhosis, 6 with hepatoma, 19 with malignant tumors, 10 with T. B pleurisy, 10 with inflammation were examined for lactic dehydrogenase, abenosine deaminase, fibrin/fibrinogen dedradation products, iron binding protein and C-reactive protein. The paramaters in T. B pleurisy, inflammation, malignant tumors, hepatoma, cirrhsis, hepatitis were evaluated. The paramaters were not obviously different among T. B inflammation, malignant tumors or bepatoma and cirrhosis, hepatitis (p>0.05). But they were signicantly higher in T. B, inflammation, malignant tumors than in cirrhosis hepatoma (p<0.01). The concentration o CRP in inflammation was higher than those in others.

     

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