大豆蛋白对大鼠抗氧化能力的影响

李季芳; 蒋卓勤; 熊俊艳; 黎艺

doi:10.3969/j.issn.2095-5227.2013.07.034

大豆蛋白对大鼠抗氧化能力的影响

Effect of soy protein on anti-oxidation in rats

摘要

摘要: 目的观察大豆蛋白对大鼠抗氧化能力的影响。方法 SPF级雄性SD大鼠24只，进食基础饲料适应性喂养2周，随机分为2组：大豆蛋白组和酪蛋白组，每组各12只，进食实验饲料28 d。测定大鼠血清及肝脏中各种抗氧化能力指标。结果酪蛋白组和大豆蛋白组大鼠肝脏组织的总抗氧化能力(total antioxidant capacity，T-AOC)、谷胱甘肽过氧化物酶(glutathione peroxidase，GSH-Px)、超氧化物歧化酶(superoxide dismutase，SOD)、过氧化氢酶(catalase，CAT)活性，丙二醛(malondialdehyde，MDA)水平差异无统计学意义(P＞ 0.05)。酪蛋白组和大豆蛋白组大鼠血清中T-AOC、GSH-Px、SOD、CAT活性差异无统计学意义(P＞ 0.05)，大豆蛋白组大鼠血清中MDA水平低于酪蛋白组(P＜ 0.05)。结论大豆蛋白对大鼠抗脂质氧化能力有改善作用。

Abstract: Objective To observe the effect of soy protein on anti-oxidation in rats. Methods Two weeks after 24 SPF male SD rats were fed with a common chow followed by experiment diets for 28 days, they were randomly divided into soy protein group and casein group. Different anti-oxidation parameters were measured in serum and liver tissue from rats. Results No significant difference was found in liver tissue levels of T-AOC, GSH-Px, SOD, CAT and MDA and in serum activity of T-AOC, GSH-Px, SOD and CAT between the two groups (P＞ 0.05). The serum MDA level was lower in soy protein group than in casein group (P＜ 0.05). Conclusion Soy protein can improve the anti-oxidation of lipid in rats.

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