王伟君, 乔广宇, 尚爱加, 佟怀宇, 高海浩, 潘隆盛. 保留寰椎后弓的小脑扁桃体下疝畸形手术应用及疗效分析[J]. 解放军医学院学报, 2015, 36(7): 702-705. DOI: 10.3969/j.issn.2095-5227.2015.07.017
引用本文: 王伟君, 乔广宇, 尚爱加, 佟怀宇, 高海浩, 潘隆盛. 保留寰椎后弓的小脑扁桃体下疝畸形手术应用及疗效分析[J]. 解放军医学院学报, 2015, 36(7): 702-705. DOI: 10.3969/j.issn.2095-5227.2015.07.017
WANG Weijun, QIAO Guangyu, SHANG Aijia, TONG Huaiyu, GAO Haihao, PAN Longsheng. Surgical application and efficacy of retained arcus posterior atlantis for chiari malformation typeⅠ[J]. ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL, 2015, 36(7): 702-705. DOI: 10.3969/j.issn.2095-5227.2015.07.017
Citation: WANG Weijun, QIAO Guangyu, SHANG Aijia, TONG Huaiyu, GAO Haihao, PAN Longsheng. Surgical application and efficacy of retained arcus posterior atlantis for chiari malformation typeⅠ[J]. ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL, 2015, 36(7): 702-705. DOI: 10.3969/j.issn.2095-5227.2015.07.017

保留寰椎后弓的小脑扁桃体下疝畸形手术应用及疗效分析

Surgical application and efficacy of retained arcus posterior atlantis for chiari malformation typeⅠ

  • 摘要: 目的 探讨保留寰椎后弓的小骨窗减压、枕大池成形显微外科手术方法对小脑扁桃体下疝畸形Ⅰ型(chiari malformation typeⅠ,CMI)的临床治疗效果。 方法 我院于2013年3月- 2014年6月对23例具有完整寰椎后弓的CMI病例,采用枕外粗隆下2 cm至颈2棘突上缘约5 cm后正中直切口,保留寰椎后弓的后颅窝小骨窗减压、枕大池成形术(探查四脑室底枕大池重建,小脑扁桃体下疝切除、硬脑膜扩大修补),观察术后1周、3个月及远期疗效,并进行Karnofsky功能状态评分(Karnofsky performance status scale,KPS)。 结果 术后1周患者神经症状改善19例,4例无明显变化,平均KPS评分由术前53.5±9.8分提高到66.52±9.8分(P< 0.00)。术后3个月复查,6例患者痊愈,12例症状改善明显,3例缓解,1例症状无明显变化,1例加重,较术后1周改善情况有统计学差异(P< 0.03)。术后3个月KPS评分提高至85.2±14.7分(P< 0.00)。术后3个月~ 2年的随访中,小脑扁桃体下疝和脊髓空洞消失或明显缩小。 结论 保留寰椎后弓的小骨窗减压、枕大池成形术临床效果较好,是治疗CMI安全、有效的手术方法。

     

    Abstract: Objective To discuss the efficacy of microsurgical approaches of small-bone-window posterior fossa decompression and cisterna magna angioplasty with conserved posterior arch of atlas in treatment of chiari malformation typeⅠ. Methods Twentythree cases with arcus posterior atlantis in the treatment of CMI in Chinese PLA General Hospital from March 2013 to June 2014 were selected. Patients had undergone small-window posterior fossa decompression and cisterna magna angioplasty with conserved posterior arch of atlas through posterior midline approach (from 2 cm under inion to 5 cm on C2 spinous processes), and the cisterna magna was reconstructed, the cerebellar tonsil subpial was resected, and duraplasty was performed. The long-term efficacy was observed for 1 week and 3 months postoperatively, and KPS score was used to evaluate the conditions after operation. Results One week after operation, the neurological condition was improved in 19 cases, while 4 cases had no change. The average KPS score increased from (53.5±9.8) preoperatively to (66.52±9.8) postoperatively (P< 0.00). And 3 months after operation, 6 cases were cured, 3 cases were relieved, 1 case had no change and 1 case was exacerbation, which was better than 1 week postoperative condition (P< 0.03). The average KPS score of 3 months after operation increased to 85.2±14.7 (P< 0.00). Cerebellar tonsillar hernia and syringomyelia shrank or disappeared obviously within 2-year follow-up. Conclusion The microsurgical approaches of small-window posterior fossa decompression and cistern magna angioplasty with conserved posterior arch of atlas shows excellent efficacy and less complication in treating chiari malformation typeⅠ.

     

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