Abstract: Objective To analyze the clinical characteristics of 5 cases with Ebola hemorrhagic fever in Liberia, and improve the understanding of Ebola virus disease. Methods Clinical data about 5 cases with confrmed Ebola hemorrhagic fever admitted to Chinese ETU in Liberia from January to March in 2015, including medical history, signs and treatment, were analyzed. Results There were 2 male patients and 3 female patients with an average age of 46. Treatments were taken, including supplement of water electrolyte, relieve gastrointestinal reaction relief and fever control. Of the 5 cases, 3 cases were treated and 2 cases died. Conclusion The clinical manifestation of Ebola hemorrhagic fever has no specificity, and the diagnosis is rather difficult with clinical manifestation alone, laboratory examination should be taken for early diagnosis. Patients in special geography or environment who show fever performance should be diagnosed and treated timely combining with laboratory examination.