EB病毒编码microRNAs生物学功能的研究进展
Research advances in biological function of Epstein-Barr virus encoded microRNAs
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摘要: 研究表明EB病毒作为人类主要的致癌病毒,可通过编码miRNAs参与病毒感染、细胞凋亡、肿瘤侵袭与转移等过程。本文综述了EBV miRNAs的合成及作用机制,旨在为EB病毒相关疾病研究提供新的信息。Abstract: Numerous studies have demonstrated that Epstein-Barr virus, a vital carcinogenic virus of human cancer, is involved in viral infection, apoptosis, tumor invasion and metastasis through coding microRNA (miRNA). In this review, we summarize the synthesis of EBV encoded miRNAs and their functional mechanisms, which may provide new target and strategies for the treatment of EB virus related diseases.