Background  Allergic rhinitis and/or asthma is one of the most common types of allergic diseases. However, the positive rate of various inhaled allergens, the mean level of specific IgE (sIgE), the distribution characteristics of different levels of sIgE, and the relationship between sIgE and related indicators are not clear.

  Objective  To observe the levels of different allergen sIgE and their relationships with related indexes.

  Methods  A total of 1 101 patients with allergic rhinitis and/or allergic asthma admitted to the allergic reaction clinic of our hospital from October 2016 to January 2020 were selected. The positive rate of serum sIgE, average level of sIgE, distribution characteristics of different levels of sIgE and the correlation between sIgE and related indicators were observed.

  Results  There were 378 males with an average age of (37.42 ± 16.78) years and 723 females with an average age of (38.79 ± 14.62) years. The positive rate of autumn pollen allergy patients was the highest (35.79%). The level of sIgE was significantly higher than other inhaled allergens (P ＜ 0.05), and the proportion of extremely severe allergy patients was the highest (45.18%). The positive rate of dust mite sIgE was 34.51%, which was the most common perennial allergen. The level of sIgE distribution of dust mite was similar to mold. The sIgE levels of dog dander and mixed mold were both positively correlated with age (r=0.231, P=0.005; r=0.216, P=0.000), while the sIgE levels of amaranth pollen and autumn pollen were negatively correlated with age (r=-0.147, -0.146; all P ＜ 0.05).

  Conclusion  Autumn pollen and dust mite are the most common seasonal and perennial allergens, respectively. The levels of different allergen sIgE in patients have great differences, but most of them are not affected by gender and age.