Abstract: Objective To analyze the adjuvant therapeutic effect of individualized nutrition support on ulcerative colitis（UC）. Methods Sixty UC patients who were retrospectively analyzed.The patients were divided into treatment group and control group and changes in their nutritional condition were assessed. Results The UC,a recurrent type,was severer in treatment group than in control group and the number of UC patients with their whole colon involved was greater than that of those with their partial colon involved.The total protein and albumin levels were significantly lower while the nutritional risk score（NRS） was significantly higher in treatment group than in control group（P＜0.05）.The BMI and total protein level were significantly lower in control group after routine clinical treatment than in treatment group after combined simple clinical and individualized nutritional support treatment（P＜0.05）. Conclusion Nutritional risks should be examined in patients with severe UC.Patients with severe UC should receive rational nutritional support which can improve their nutritional condition.